Phytochemistry


    Natural Product Chemistry, Medicinal Chemistry, For more information please visit: https://sites.google.com/view/kapilslab/home
  • B.Sc. Chemistry, Physics, Mathematics
  • M.Sc. Pharmaceutical Chemistry
  • Ph.D. Chemical Sciences
  • CSIR-Central Drug Research Institute, Lucknow, India , - Project Assistant-II (March 2010- July 2012 )
  • CSIR-Central Drug Research Institute, Lucknow, India , - CSIR-Junior Research Fellow (July 2012- July 2014 )
  • CSIR-Central Drug Research Institute, Lucknow, India, - CSIR-Senior Research Fellow (July 2014- January 2017 )
  • Jubilant Chemsys Pvt. Ltd., Noida, India, - Research Scientist-II (March 2017- February 2019 )
  • Yunnan University, Kunming, China, - Postdoctoral Research Fellow (March 2019- November 2019 )
  • CSIR-CIMAP, Lucknow, - Scientist (November 2019- till date )
  • Best Poster Award,by HNBGU, Dehradun, India in 2012
  • Technology Award,by CSIR-CDRI, Lucknow in 2019
  • Incentive Award,by CSIR-CDRI, Lucknow in 2020
  • Singh, A.; Singh, P.; Kumar, B.; Kumar, S.; Dev, K.; Maurya, R.,. Detection of flavonoids from Spinacia oleracea leaves using HPLC-ESI-QTOF-MS/MS and UPLCQqQLIT-MS/MS techniques. Natural Products Research 2018
  • Choudhary, D.; Kothari, P.; Tripathi, A. K.; Singh, S.; Adhikary, S.; Ahmad, N.; Kumar, S.; Dev, K.; Mishra, V. K.; Shukla, S.; Maurya, R.; Mishra, P. R.; Trivedi, R.,. Spinacia oleracea extract attenuates disease progression and sub-chondral bone changes in monosodium iodoacetate induced osteoarthritis in rats. BMC Complementary and Alternative Medicine 2018
  • Maurya S. W.; Dev, K.; Prakash, R.; John, A. A.; Siddiqui, I. R.; Singh, D.; Maurya, R., . Design and synthesis of indolyl chalcone analogues and evaluation of their osteogenic activity. Journal of Pharmacology and Pharmaceutical Research 2018
  • Gautam Brahmachari, Kapil Dev; E. Ramakrishna; Rakesh Maurya;. Glucose Transporter 4 (GLUT4) Translocation Activators from Nature. Discovery and Development of Anti-Diabetic Agents from Natural Products: Natural Product Drug Discovery, Elsevier, ISBN: 978-0-128-09692-5, 2016, Chapter 4, pp 113-145 2017
  • Prof. Gautam Brahmachari; Kapil Dev; Rakesh Maurya;. Marine-Derived Anti-Alzheimer’s Agents of Promise. Neuroprotective Natural Products: Clinical Aspects and Mode of Action Wiley-VCH, ISBN: 978-3-527-34186-3, 2017, Chapter 7, pp 153-184 2017
  • Dev, K.; Srivastava, S.; Bisht, R. . Chemical and Pharmacological Profile of Psidium guajava: A Mini Review. Indian Forester Journal 2022
  • Pandey, J.; Dev, K.; Chattopadhyay, S.; Kadan, S.; Sharma, T.; Sanyal, S.; Siddiqi, M. I.; Zaid, I.; & Tamrakar, A.. ß-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells. Molecules 2021
  • Trivedi, R.; Adhikary, S.; Kothari, P.; Ahmad, N.; Mittapelly, N.; Pandey, G.; Shukla, M.; Kumar, S.; Dev, K.; Choudhary, D.; Maurya, R.; Lal, J.; Mishra, P. R.,. Self-emulsifying formulation of Spinacia oleracea reduces the dose and escalates bioavailability of bioactive compounds to accelerate fracture repair in rats. Clinical Phytoscience 2020
  • Dev, K.; Ramakrishna, E.; Kothari, P.; Tripathi, A. K.; Trivedi, R. and Maurya, R.. Phytochemical investigation of Kigelia pinnata leaves and identification of osteogenic agents. Medicinal Chemistry Research, 2017, 26, 940-940 2017
  • Singh, K. B.; Dixit, M.; Dev, K.; Rakesh Maurya; and Divya Singh.. Formononetin, a methoxy isoflavone, enhances bone regeneration in a mouse model of cortical bone defect.. British Journal of Nutrition, 117, 1511-1522 2017
  • Dev, K.; Ramakrishna, E.; Maurya, S. W.; Siddiqui, I. R.; Kant, R. and Maurya, R.. Ugi three-component reaction of alcohols, amines and isocyanides: A new approach to the synthesis of cyclic amidines. Tetrahedron Letters , 58, 1202-1206, 2017
  • Dev, K.; Ramakrishna, E.; Maurya, S. W.; Siddiqui, I. R. and Maurya, R.. Hypervalent iodine (III)-mediated oxidation of aryl sulfonylhydrazones: A facile synthesis of N-aroyl-N'-acyl arylsulfonylhydrazides. Tetrahedron Letters, 58, 570-573, 2017
  • Dev, K.; Khan, M. F.; Lahiri, S.; Dixit, M.; Trivedi, R.; Singh, D. and Maurya, R.. Osteogenic activity of natural diterpenoids isolated from Cupressus sempervirens fruits in calvarial derived osteoblast cells via differentiation and mineralization.. Phytomedicine 21, 1794–1800, 2014
  • Dev, K.; Khan, M. F.; Lahiri, S.; Dixit, M.; Trivedi, R.; Singh, D. and Maurya, R.. Osteogenic activity of natural diterpenoids isolated from Cupressus sempervirens fruits in calvarial derived osteoblast cells via differentiation and mineralization.. Phytomedicine 21, 1794–1800, 2014
  • Akansha Mishra, Khushbu Sharma, Jyotsana Pandey, Kapil Dev, Sleman Kadan, Mahendra Sahai, Ishbal Ahmad, Arvind K. Srivastava, Akhilesh K. Tamrakar, Hilal Zaid, Rakesh Maurya. Tinosporaside from Tinospora cordifolia Encourages Skeletal Muscle Glucose Transport through Both PI-3-Kinase- and AMPK-Dependent Mechanisms. Molecules 28(2), 483, 2023
  • Kapil Dev, Shraddha Srivastava, Rohit Bisht. Chemical and Pharmacological Profile of Psidium guajava: A Mini Review. Indian Forester Journal, 148 (4), 245-255, 2022
  • Maurya, S. W.; Dev, K.; Singh, K. B.; Rai, R.; Siddiqui, I. R.; Singh, D.; Maurya, R.. Synthesis and biological evaluation of heterocyclic analogues of pregnenolone as novel anti-osteoporotic agents. Bioorganic & Medicinal Chemistry Letters 27, 1390-1396, 2017
  • Porwal, K.; Pal, S.; Dev, K.; China, S. P.; Kumar, Y.; Singh, C.; Barbhuyan, T.; Sinha, N.; Sanyal, S.; Trivedi, A. K.; Maurya, R. and Chattopadhyay, N.. Guava fruit extract and its triterpene constituents have osteoanabolic effect: stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/ß-catenin signalling. The Journal of Nutritional Biochemistry 44, 22-34, 2017
  • Adhikary, S.; Choudhary, D.; Ahmad, N.; Kumar, S.; Dev, K.; Mittapelly, N.; Pandey, G.; Mishra, P. R.; Maurya, R.; Trivedi, R.,. Dried and free flowing granules of Spinacia oleracea accelerate bone regeneration and alleviate post-menopausal osteoporosis. Menopause, 24, 686-698, 2017
  • Gautam, J.; Khedgikar, V.; Kushwaha, P.; Choudhary, D.; Nagar, G. K.; Dev, K.; Dixit, P.; Singh, D.; Maurya, R.; Trivedi, R.. Formononetin, an isoflavone, activates AMPK/ß-catenin signaling to inhibit adipogenesis and rescues C57BL/6 mice against high fat diet induced obesity and bone loss. British Journal of Nutrition, 117, 645-661, 2017
  • Srivastava, A.; Singh, H.; Mishra, R.; Dev, K.; Tandon, P.; Maurya, R.,. Structural insights, protein-ligand interactions and spectroscopic characterization of isoformononetin. Journal of Molecular Structure 1133, 479-491, 2017
  • Singh, H.; Singh, S.; Srivastava, A.; Tandon, P.; Bharti, P.; Kumar, S.; Dev, K.; Maurya, R.. Study of hydrogen?bonding, vibrational dynamics and structure-activity relationship of genistein using spectroscopic techniques coupled with DFT. Journal of Molecular Structure 1133, 929-939, 2017
  • Mittal, M.; Pal, S.; China, S. P.; Porwal, K.; Dev, K.; Shrivastava, R.; Raju, K. S.; Rashid, M.; Trivedi, A. K.; Sanyal, S.; Wahajuddin, M.; Bhaduria, S.; Maurya, R.; Chattopadhyay, N.. Pharmacological activation of aldehyde dehydrogenase 2 promotes osteoblast differentiation via bone morphogenetic protein-2 and induces bone anabolic effect. Toxicology and Applied Pharmacology 316, 63-73, 2017
  • Mansoori, M. N.; Tyagi, A. M.; Shukla, P.; Srivastava, K.; Dev, K.; Chillara, R.; Maurya, R.; Singh, D.. Methoxy isoflavone formononetin and isoformononetin inhibit the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions. Menopause 23, 565-576, 2016
  • Srivastava, A.; Mishra, R.; Kumar, S.; Dev, K.; Tandon, P.; Maurya, R.. Molecular structure, spectral investigation (1H NMR, 13C NMR, UV–Visible, FT-IR, FT-Raman), NBO, intramolecular hydrogen bonding, chemical reactivity and first hyperpolarizability analysis of formononetin [7-hydroxy-3(4-methoxyphenyl)chromone]: A quantum chemical study. Journal of Molecular Structure 1084, 55-73, 2015
  • Taneja, I.; Raju, K. S. R.; Mittal, M.; Dev, K.; Khan, M. F.; Maurya, R.; Wahajuddin, M.. Bioavailability, plasma protein binding and metabolic stability studies of ALDH2 activator, alda-1, using validated LC-ESI-MS/MS method in rat plasma. RSC Advances 5, 54395-54402, 2015
  • Dev, K. and Maurya, R.. Facile synthesis of 11-aryl-6H-isoindolo[2,1-a]-indol-6-ones via hypervalent iodine(III)-promoted cascade cyclization.. RSC Advances 5, 13102-13106, 2015
  • Khan, M. F.; Maurya, C. K.; Dev, K.; Arha, D.; Rai, A. K.; Tamrakar, A. K. and Maurya, R.. Design and synthesis of lupeol analogues and their glucose uptake stimulatory effect in L6 skeletal muscle cells.. Bioorganic & Medicinal Chemistry Letters 24, 2674-2679, 2014
  • Omeje, E. O.; Khan, M. P.; Osadebe, P. O.; Tewari, D.; Khan, M. F.; Dev, K.; Maurya, R. and Chattopadhyay, N.. Analysis of constituents of the eastern Nigeria mistletoe, Loranthus micranthus Linn revealed presence of new classes of osteogenic compounds.. Journal of Ethnopharmacology 151, 643–651, 2014
  • Yadav, D. K.; Singh, N.; Dev, K.; Sharma, R.; Sahai, M.; Palit, G. and Maurya, R.. Anti-ulcer constituents of Annona squamosa twigs.. Fitoterapia 82, 666-675, 2011
  • Srivastava, S.; Mishra, D.; Bisht, R.; Savita, K.; Singh, K.; Rani, P.; Chanda, D.; Dev, K.*. Psiguanol, a novel a-pyrone derivative from Psidium guajava leaves and vasorelaxant activity in rat aorta cells through intracellular cGMP-dependent opening of calcium-activated potassium channels. Natural Products Research 2024
  • Mugale, M. N.; Dev K.; More, B. S.; Mishra, S. V.; Washimkar, R. Kaveri.; Singh, K.; Maurya, R.; Rath, S. K.; Chattopadhyay, D.; Chattopadhyay, N.. A comprehensive review on preclinical safety and toxicity of medicinal plants. Clinical Complementary Medicine and Pharmacology 2024
  • Maurya, P.; Dwivedi, N.; Mazeed, A.; Kumar, D.; Kumar, B.; Channotiya, C. S.; Dev, K., Suryavanshi, P.. Allelopathic weed management in wheat (Triticum aestivum L.) through essential oil emulsions and aqueous botanical extracts based novel bioherbicides.. Journal of Plant Diseases and Protection 2024
  • Gupta, R. K.; Singh, S.; Chanotiya, C. S.; Dev, K.; Trivedi, P. K.; Singh, A.. Diversity and functional characterization of endophytes in two contrasting cultivars of Ocimum sanctum: Insights from culture-based and metagenomic approaches. Journal of Plant Growth Regulation 2024
  • Singh, K.; Yadav, A.; Khan, S.; Shukla, A.; Alam, M.; Verma, A. K.; Tiwari, N.; Khan, F.; Yadav, P. N.; Dev, K.*. Baicalein isolated from Oroxylum indicum acts as a potent µ- and ?-opioid receptor antagonist agent via the reversal of agonist-mediated cAMP inhibition. Natural Product Research 2024

Copyright © 2022 CSIR-CIMAP. All rights reserved