Name : Ashish Sharma Designation : Scientist Address : abcd E. mail : ashishsharma@cimap.res.in Contact No : 7388939615 Epabx No. : 05222718518 Download Resume Area of Specialization The plant, the world's greenest chemist, is a dynamic system with an ever-evolving genome; it harnesses solar energy to synthesize a wide range of natural products used in medicine and industry. Secondary metabolites synthesized by medicinal and aromatic plants (MAPs) have numerous therapeutic importance for human health and well-being. The main aim of the lab is to enhance low-yield and high-value molecules of MAPs. Small molecules like small peptides, miRNA, miPEP, microProtein etc. have been identified and have proven their essential role in plant biology. However, they still need to be identified and characterized in MAPs. Our lab is interested in elucidating the role of such small molecules in enhancing secondary plant products. The lab aims to use biotechnological tools, enhance medicinal compounds' production in cost-effective systems, and increase nutritional compounds from promising crops. Our group is also exploring novel microproteins/sORF having regulatory roles in plant growth and development. Education B.Sc. Botany, Chemistry M.Sc. Biochemistry Ph.D. Biological Science Post Doctoral Plant Molecular Biology Academic/Research Experience CSIR- NBRI, Lucknow, - Ph.D. (2016- 2020 ) University of Copenhagen, Denmark , - Post Doctoral (2022- 2023 ) CSIR- CIMAP, Lucknow, - DST-Inspire Faculty (2023- 2024 ) CSIR- CIMAP, Lucknow, Biotechnology Division - Scientist (July 2024- till date ) Honours and Awards CSIR-CIMAP Annual Day award, Outstanding research publication,by CSIR- CIMAP in 2024 CSIR-CIMAP Annual Day award, Outstanding research publication,by CSIR- CIMAP in 2023 DST- Inspire Faculty Award,by Department of Science and technology, Gov. of India in 2022 Teacher of the Year (2022) ,by University of Copenhagen, Plant Science Centre, Denmark. in 2022 Best Oral Presentation ,by in Plant Specialized Metabolism & Metabolic Engineering Virtual Conference at CSIR-CIMAP in 2020 Best Poster Presentation ,by in 4th International Plant Physiology at CSIR-NBRI in 2018 CSIR-SRF fellowship ,by CSIR in 2018 ICAR JRF fellowship,by ICAR in 2014 GATE fellowship ,by IIT in 2013 Publication Kumar, R.S., Sinha, H., Datta, T., Sharma, A. and Trivedi, P.K.. Genome-Editing Tools for Engineering of MicroRNAs and Their Encoded Peptides, miPEPs, in Plants. Applications of Genome Engineering in Plants 2024 Edwards, A., Chiurazzi, M.J., Blaakmeer, A., Vittozzi, Y., Sharma, A., Matton, S., Kruusvee, V., Straub, D., Sessa, G., Carabelli, M., Morelli, G. and Wenkel S. A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development. eLife 2024 Gaddam, S.R., Sharma, A., Bhatia, C. and Trivedi, P.K. A network comprising ELONGATED HYPOCOTYL5, microRNA397b, and auxin-associated factors regulates root hair growth in Arabidopsis. Plant Physiology 2024 Sharma, A. Anyatama, A., Gautam, H., Gaddam, S.R., Singh, D., Sinha, H. and Trivedi, P.K. Enhancing Nutritional Quality in Plants using Complementary Peptide for Sustainable Agriculture. Plant Physiology 2024 Gautam, H., Sharma, A. and Trivedi, P.K . Plant microProteins and miPEPs: Small molecules with much bigger roles. Plant Science 2023 Gautam, H., Sharma, A. and Trivedi, P.K. The role of flavonols in insect resistance and stress response. Current Opinion in Plant Biology 2023 Gaddam, S.R., Sharma, A. and Trivedi, P.K. miR397b-LAC2 module regulates cadmium stress response by coordinating root lignification and copper homeostasis in Arabidopsis thaliana. Journal of Hazardous Materials 2023 Sharma, A., Gautam, H. and Trivedi, P.K. Genetic manipulation of microRNAs: approaches and limitations. . Journal of Plant Biochemistry and Biotechnology 2023 Sharma, A., Badola, P.K., Gautam, H., Gaddam, S.R. and Trivedi, P.K. HY5 regulates light-dependent expression and accumulation of miR858a-encoded peptide, miPEP858a. Biochemical and Biophysical Research Communications 2022 Badola, P.K.#, Sharma, A.#, Gautam, H. and Trivedi, P.K. (#Contributed equally). MicroRNA858a, its encoded peptide, and phytosulfokine regulate Arabidopsis growth and development. Plant Physiology 2022 Gaddam, S.R., Bhatia, C., Gautam, H., Pathak, P.K., Sharma, A., Saxena, G. and Trivedi, P.K. Ethylene regulates miRNA-mediated lignin biosynthesis and leaf serration in Arabidopsis thaliana. Biochemical and Biophysical Research Communications 2022 Sharma, A., Badola, P.K., Gautam, H. and Trivedi, P.K. Heterologous expression of Arabidopsis miR858 modulates biosynthesis of secondary metabolites and affects drought tolerance in tobacco. Plant Cell, Tissue and Organ Culture 2022 Sharma, A., Badola, P.K. and Trivedi, P.K . CRISPR-Cas9 System for Agriculture Crop Improvement. Genome engineering for crop improvement 2021 Gaddam, S.R., Bhatia, C., Sharma, A., Badola, P.K., Saxena, G. and Trivedi, P.K. miR775 integrates light, sucrose and auxin associated pathways to regulate root growth in Arabidopsis thaliana. Plant Science 2021 Sharma, A., Badola, P.K., Bhatia, C., Sharma, D. and Trivedi, P.K. Primary transcript of miR858 encodes regulatory peptide and controls flavonoid biosynthesis and development in Arabidopsis. Nature Plants 2020 Sharma, D., Tiwari, M., Pandey, A., Bhatia, C., Sharma, A. and Trivedi, P.K. MicroRNA858 is a potential regulator of phenylpropanoid pathway and plant development. Plant Physiology 2016 Patents File No Title Inventors Patent No. Abstract