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CSIR-CIMAP Research Centre, Hyderabad


Introduction:

The Hyderabad Research Centre was established in July 1982 on 12-hectare area as the regional node of CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow for showcasing and promoting CIMAP's green technologies in Deccan Plateau. The Centre has been in the forefront in developing farmer-friendly, sustainable production, essential oil distillation technologies and high yielding varieties of economically important medicinal and aromatic plants (MAPs) with export potential under resource constraint conditions for transforming wastelands and drylands into ecofriendly, profitable green herbal farms. The Centre introduced and acclimatized number of MAPs in semi-arid tropics of Deccan Plateau and promoted largescale cultivation through mission mode approach. The Centre is disseminating CIMAP's technologies through awareness camps, training programs, exhibitions, media broadcasts and reports.

The Centre has developed agro-technologies under irrigated and rainfed conditions for aromatic grasses (including Cymbopogon winterianus, C. flexuosus, C. citratus and C. nardus), rose-scented geranium (Pelargonium sp.), menthol mint (Mentha arvensis), lemon-scented gum (Eucalyptus citriodora), basils (Ocimum basilicum, O. sanctum), and medicinal crops like ashwagandha (Withania somnifera), periwinkle (Catharanthus roseus), king of bitters (Andrographis paniculate), ambrette (Abelmoschus moschatus) and itching bean (Mucuna pruriens). Among these, king of bitters, periwinkle, ashwagandha, palmarosa, lemon-scented gum and lemongrass are amenable for rainfed cultivation.

The R&D endeavors coupled with extension activities of the Centre led to large-scale cultivation of MAPs. In Andhra Pradesh, >5000 farmers are cultivating >9500 hectares using CIMAP's varieties and technologies. Due to the initiative taken by the Centre, tribal farmers of East Godavari and Visakhapatnam districts are cultivating citronella, lemongrass, yarrow root and long pepper under rainfed condition. Small and marginal farmers of drought prone Anantapur district are cultivating winter cherry under rainfed condition partially replacing traditional groundnut that has become less remunerative. The Centre has established market linkages to these farmers. Owing to availability of quality herbals, the Centre encouraged entrepreneurs to launch herbal extraction units, marketing agencies, distillation unit manufacturing companies leading to business expansion and employment generation in the region. The Centre is helping schools and colleges to establish herbal gardens and is creating awareness in general public concerning the importance of medicinal plants and the necessity to conserve them for posterity. The awareness created by the Centre led to starting of courses on MAPs in the local universities and Greater Hyderabad Municipal Corporation established Botanical Garden with medicinal and aromatic plants recently.

The Centre continued to innovate to excel in MAPs green technologies and endeavour to be a friend of the farmer, a facilitator to industry- farmer linkages and a partner in the development of the region. The Centre is striving to be the preferred destination of farmers and industry to discover new dimensions of opportunities in MAPs sector.


Agrotechnologies developed:

  • The Centre has developed agro-technologies under irrigated and rainfed conditions for aromatic grasses, menthol mint, lemon-scented gum, basils, jamrosa, davana and medicinal crops like winter cherry, Chlorophytum, periwinkle, king of bitters, ambrette and itching bean. Among these, king of bitters, periwinkle, winter cherry, palmarosa, lemon-scented gum and lemongrass are amenable for rainfed cultivation.
    1. Introduced intercropping of lemon scented basil in lemongrass in semi arid tropic region in order to get additional income.
    2. A new chemotype of Ocimum tenuiflorum containing essential oil rich in methyl eugenol (>70%) was developed.
    3. Harvest of secondary branches was shown to produce higher essential oil yield of methyl eugenol rich O. tenuiflorum.Pre-flowering harvesting of O. gratissimum was shown to produce higher essential oil and eugenol yields.
    4. Agronomic practices (size of planting material, N and FYM requirement, nipping of inflorescence, cropping system, etc.) were developed for higher safed musli tuber yield in south Indian plains.
    5. Lemongrass cv. Krishna produced good quality oil (> 75% citral) when it was harvested four times in a year in south Indian plains.
    6. High density planting and deep tillage was shown to significantly improve root yield of ashwagandha
    7. Curtailment of 25% light during summer season coupled with drip irrigation was shown to remarkably improve essential oil yield of rose-scented geranium beside significant water economy.
    8. Harvesting of shoots containing 4 fully expanded leaves of rose-scented geranium gave higher essential oil yield and net income.
    9. Intercropping ambrette with green gram, black gram and cluster bean did not reduce the seed yield of ambrette and produced bonus yields of legumes.
    10. Sowing the seeds at 5 cm depth gave maximum seed yield compared to 2.5 or 7.5 cm sowing depths in Mucuna.
    11. Row spacing of 60 x 30 cm or 90 x 30 cm and application of 5 t/ha vermicompost produced the highest seed yield of Mucuna.
    12. Significantly higher seed yield of Mucuna was recorded with 100 kg N/ha application.
    13. Application of 60 kg P and 60 kg K/ha significantly increased the seed yield of Mucuna.
    14. Combined application of 20 t FYM + NPK produced the maximum shoot biomass yield of Andrographis.
    15. Co-cultivation of Eucalyptus citriodora and Pelargonium sp. was shown to be advantageous in south Indian plains.

2021:

  1. Yakaiah Chinthala, A. Niranjana Kumar, K.V.N.S. Srinivas, J. Kotesh Kumar, Srinivas Chinde, Paramjit Grover. Synthesis of Novel Anticancer Derivatives of Rare Iso-Flavonone Scillascillin from a new species Ledebouria hyderabadensis. Journal of Medicinal and Aromatic Plant Sciences, 2021
  2. Komuraiah Buduma, Niranjana Kumar A, Satya Srinivas KVN,,Kotesh Kumar J, Srinivas Chinde, Anand Kumar Domatti, Yogesh Kumar, Paramjit Grover, Ashok Tiwari, Feroz Khan. Synthesis and bioactivity evaluation of eugenol hybrids obtained by Mannich and 1,3 dipolar cycloaddition reactions. J Heterocyclic Chem. 2021;1–12. https://doi.org/10.1002/jhet.4331
  3. Devendar Ponnam, Niranjana Kumar Arigari, Satya Srinivas Kalvagunta Venkata Naga, Kotesh Kumar Jonnala, Shilpi Singh, Abha Meena, Pallavi Misra, Suaib Luqman. Synthesis of non-toxic anticancer active forskolin-indoletriazole conjugates along with their in silico succinate dehydrogenase inhibition studies. J Heterocyclic Chem. 2021;1–12. https://doi.org/10.1002/jhet.4332.

2020:

  1. Anthati Mastan, Chikkarasanahalli Shivegowda, Vivek Babu, Channayya Hiremath, KVNS Srinivas, Arigari Niranjan Kumar, Jonnala Kotesh Kumar. Treatments with native Coleus forskohlii endophytes improve fitness and secondary metabolite production of some medicinal and aromatic plants. International Microbiology, 2020, 23(2):345-354.
  2. Channayya Hiremath, Manoj K Yadav, M.R. Swamy Gowda, A. Niranjan kumar, K.V.N. S. Srinivas. Influence of growth stage on essential oil content and major chemical constituents of Artemisia pallens Bess. Trends in Phytochemical Research, 2020, 4(2), 85-92.
  3. Channayya Hiremath, Sundaresan V, Baskaran K, Amit Kumar, Yogendra Nd, Manoj K Yadav, Ram Swaroop Verma, Satya Srinivas, Kotesh Kumar, Niranjan Kumar, Alok Kalra, Anil Kumar Tripathi (2020). Linalool rich variety CIM-Sukhda of Ocimum basilicum. Journal of Medicinal and Aromatic Plant Sciences, 2020, 42(1-2), 68-72.
  4. Kulkarni Rn, Baskaran K, Sundaresan V, Channayya Hiremath, Yogendra Nd, Manoj K Yadav, Satya Srinivas, Kotesh Kumar, Niranjan Kumar, Rajendra Chandra Padlia, Amit Kumar, Alok Kalra, Anil Kumar Tripathi. A Geraniol rich lemongrass variety (Cymbopogon flexuosus (Steud.) Wats.): CIM-Atal. Journal of Medicinal and Aromatic Plant Sciences, 2020, 42(1-2), 64-67.
  5. Yogendra N D, M. Nazeer, Channayya Hiremath, A. Niranjana Kumar, K.V. N. Satya Srinivas and J. Kotesh Kumar. Effect of different drying methods and storage on the volatile oil content of patchouli. India perfumer, 2020, 64(3), 19-24.

2018:

  1. G.D. Kiran Babu, Shudh Kirthi Dolma, Mohit Sharma, S.G. Eswara Reddy. Chemical composition of essential oil and oleoresins of Zingiber officinale and toxicity of extracts/essential oil against diamondback moth (Plutella xylostella). Toxin Reviews, 2018, https://doi.org/10.1080/15569543.2018.1491056.

2016:

  1. Komuraiah Buduma, Srinivas Chinde, Anand Kumar Dommati, Pooja Sharma, Aparna Shukla, Satya Srinivas K.V.N, Niranjana Kumar Arigari, Feroz Khan, Ashok Tiwari, Paramjit Grover, Kotesh Kumar Jonnala (2016). Synthesis and evaluation of Anticancer and Antiobesity activity of 1-ethoxy carbonyl-3,5-bis (3ʹ-indolyl methylene)-4-pyperidone analogues. Bioorganic and Medicinal Chemistry Letters, 2016, 26, 1633-1638.
  2. Komuraiah Buduma, Srinivas Chinde, Niranjana Kumar Arigari, Paramjit Grover, Srinivas K.V.N.S. and Kotesh Kumar Jonnala. Iodine catalyzed simple and efficient synthesis of antiproliferative 2-pyridones. Bioorganic and Medicinal Chemistry Letters, 2016, 26(9), 2159-63. http://dx.doi.org/10.1016/j.bmcl.2016.03.071.
  3. B.R. Rajeswara Rao, G. Adinarayana, A. Niranjana Kumar, D.K. Rajput, K.V. Syamasundar. Chemical-profile variations in essential oils isolated from lemongrass (Cymbopogon flexuosus) biomass and condensate wastewater by re-distillation and solvent extraction techniques. Journal of Essential Oil Research. 2016, 28 (6), 557-564.
  4. Mishra P, Kumar A, Rodrigues V, Shukla AK, Sundaresan V. 2016 Feasibility of nuclear ribosomal region ITS1 over ITS2 in barcoding taxonomically challenging genera of subtribe Cassiinae (Fabaceae) Peer J 4:e2638; DOI 10.7717/peerj.2638.
  5. Garikapati D. Kiran Babu, Aarti Sharma and Bikram Singh. Volatile Composition of Lavandula angustifolia Produced by Different Extraction Techniques. J. Essent. Oil Res. 2016, 28(6):489-500. http://dx.doi.org/10.1080/10412905.2016.1162210.
  6. G.D. Kiran Babu, Vipan Thakur and Bikram Singh. Variability in the composition of Lavandula angustifolia extracts due to extraction methods. J. Herbs Spices & Med. Pl. 2016, 22(2): 173-182. http://dx.doi.org/10.1080/10496475.2015.1136979.

2015:

  1. Pandu Sastry Kakaraparthi, K.V.N.S. Srinivas, J. Kotesh Kumar, A. Niranjana Kumar, D. K. Rajput, S. Anubala. Changes in the essential oil content and composition of palmarosa (Cymbopogon martini) harvested at different stages and short intervalsin two different seasons. Industrial Crops and Products, 2015, 69, 348–354.
  2. Pandey Pallavi, Singh Sailendra, Srinivas KVNS, Shukla Aparna, Tewari Nimisa, Gupta Namita, Vasudeva Prema, Khan Feroz, Pal Anirban, Bhakuni Rajendra Singh, Kotesh Kumar J, Suchitra Banerjee. Hairy root mediated functional derivatization of artemisinin and their bioactivity analysis. Journal of Molecular Catalysis B: Enzymatic. 2015, 113, 95-103.
  3. Yakaiah Chinthala, Sneha Thakur, Shalini Tirunagari, Srinivas Chinde, Anand kumar Domatti, Niranjana Kumar Arigari, Srinivas K.V.N.S., Sarfaraz Alam, J. Kotesh Kumar, Feroz Khan, Ashok Tiwari, Paramjit Grover. Synthesis and bioactivity screening of novel chalcone triazoles. European Journal of Medicinal Chemistry, 2015, 93, 564-73.
  4. Ponnam Devendar, Vadithe Lakshma Nayak, Dharmendra Kumar Yadav, Arigari Niranjana Kumar, Jonnala Kotesh Kumar, KVN Satya Srinivas, Balasubramanian Sridhar, Feroz Khan, Kakaraparthi Pandu Sastry and Sistla Ramakrishna. Synthesis and evaluation of anticancer activity of novel andrographolide derivatives. Medicinal Chemistry Communication, 2015, 6, 898-904.
  5. Ponnam Devendar, Arigari Niranjana Kumar, M. S. Bethu, Zehra Amtul, R. Pamanji, J. Venkateswera Rao, Ashok Kumar Tiwari, Balasubramanian Sridhar, K.V.N. Satya Srinivas and J. Kotesh Kumar. Highly selective one pot synthesis and biological evaluation of novel 3-(allyloxy)-propylidene acetals of some natural terpenoids. RSC Advances, 2015, 5, 93122 – 93130.
  6. K.P. Sastry, K. V.N. S. Srinivas, J. Kotesh Kumar, A. Niranjana Kumar and Ashish Kumar. Composition of herb and seed oil and Antimicrobial activity of the Essential oil of two varieties of Ocimum basilicum harvested at short time intervals. J. Plant Develop, 2015, 22, 59-76.
  7. Yakaiah Chinthala, Manjulatha K, Pooja Sharma, Satya Srinivas KVN, Kotesh Jonnala, Niranjana Kumar Arigari, Feroz Khan and Setty OH. Synthesis and Cytotoxicity Evaluation of Novel Andrographolide-1,2,3-Triazole Derivatives. Journal of Heterocyclic Chemistry, 2015, 53(6), 1902-1910.
  8. B.R. Rajeswara Rao, G. Adinarayana, D.K. Rajput, A. Niranjana Kumar, K.V. Syamasundar. Essential oil profiles of different parts of East Indian lemongrass {Cymbopogon flexuosus (Nees ex Steud.) Wats.}. Journal of Essential Oil Research. 2015, Vol. 27, No. 3, 225–231

2014:

  1. R. Vinod Kumar, K Babitha, L. Devi, A. Niranjan Kumar, K.V.N.S. Srinivas, J. Kotesh Kumar, S.P. Singh, P. Grover (2014). Phytochemical constituents and biological activities of Homalium zeylanicum benth. International Journal of Pharma and Bioscienes. 2014, 5(3), 176-182.
  2. K.P. Sastry, K.V.N.S. Srinivas, J. Kotesh Kumar, A. Niranjan Kumar, D.K. Rajput and U.V.M. Sharma (2014). Variation in the essential oil content and composition of Citronella (Cymbopogon winterianus Jowitt) in relation to time of harvest and weather conditions. Industrial Crops and Products. 2014, 61, 240-248.
  3. Pandu Sastry Kakaraparthi, Dharmendra Kumar Rajput, and A. Niranjana Kumar. Influence of Different Methods and Time of Post Harvest Drying on the Essential Oil Content and Composition In Eucalyptus Citriodora. Indian Journal of Applied Research. 2014, Volume-4, Issue-1, 503-507.
  4. Pandu Sastry Kakaraparthi, Dharmendra Kumar Rajput, A. Niranjana Kumar and Nivedita Influence of Different Methods and Time of Post Harvest Drying on The Essential Oil Content and Composition in Palmarosa (Cymbopogon Martinii (Roxb.) Wats. Var. Motia Burk.). Indian Journal of Applied Research. 2014, Volume: 4, Issue: 2, Feb- 5-9
  5. B. Komuraiah, Srinivas Chinde, A. Niranjana Kumar, KVNS. Srinivas, Ch. Venu, K.P. Sastry, Paramjit Grover. J. Kotesh Kumar. Isolation of phytomolecules from anticancer active extracts of Syzygium alternifolium Walp. Leaf. Pharmacognosy Journal, 2014, 6 (4), 83-85.
  6. Pandu Sastry Kakaraparthi, K.V.N.S. Srinivas, J. Kotesh Kumar, A. Niranjana Kumar, Dharmendra K. Rajput and V. Uma Maheswara Sarma. Variation in the essential oil content and composition of Citronella (Cymbopogon winterianus Jowitt) in relation to time of harvest and weather conditions. Industrial Crops and Products, 2014, 61, 240-248.
  7. Ponnam Devendar, K.V.N. Satya Srinivas, J. Kotesh Kumar, T. Sandeep Kumar, Savita Bhagel and K.P. Sastry. Phytochemical Investigation, Antioxidant and Antifungal Activities of Rhizomes of Euphorbia Fusiformis. Pharmacognosy Journal. 2014, 6(4), 78-82.
  8. M Singh and K.V.N.S. Srinivas, Influence of age of rooted cutting, nitrogen and stage of harvest on growth, yield and quality of patchouli [Pogostemoncablin (Blanco) Benth]. Journal of Spices and Aromatic Crops, 2014, 23 (1), 80-85.
  9. S. S. Kulkarni, N.S. Ravindra, K.V.N.S. Srinivas and R N. Kulkarni, In vitro chemical mutagenesis in exclusively vegetatively-propagated rose-scented geranium (Pelargonium spp.). Journal of Horticulture Science & Biotechnology, 2014, 89 (2), 173-178.
  10. Yakaiah Chinthala, Srinivas Chinde, A. Niranjana Kumar, K.V.N. Satya Srinivas, Jonnala Kotesh Kumar, Kakaraparthy Pandu Sastry, Paramjit Grover, M. Venkat Ramana. Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria Hyderabadensis. Pharmacognosy Research, 2014, 6 (4), 303-305
  11. Devendar Ponnam, Shilpi Singh, Srinivas KVNS, Luqman Suaib, Om Prakash, Zehra Amtul, Niranjan Kumar Arigari, Kotesh Kumar Jonnala, Lubna Siddiqui, Vijaya Dubey, Ashok Kumar Tiwari, Sridhar Balasubramanian, Feroz Khan. Synthesis of cyclic 1,9-acetal derivatives of Forskolin and their bioactivity evaluation, 2014, European Journal of Medicinal Chemistry. 87, 735-744.
  12. Shalini Tirunagari, Sneha Thakur, A. Niranjan Kumar, K.V.N. Satya Srinivas, J. Kotesh Kumar, K.P. Sastry, G. Krishna Mohan and M. Sandhya Rani. Phytochemical Exploration and Their Biological Evaluation from the Stem Bark of Alangium Salvifolium. International Journal of Pharma and Bioscience. 2014, 5(4), 228-234.
  13. B. Komuraiah, Srinivas Chinde, A. Niranjana Kumar, K.V.N. Satya Srinivas, Ch. Venu, J. Kotesh Kumar, K.P. Sastry and Paramjit Grover. Phytochemicals From Anticancer Active Jatropha Heynei N.P. Balakr. International Journal of Pharma and Bioscience. 2014, 5(4), 93-98.
  14. B. Lakuma Devi, K. Baitha, R. Vinod Kumar, A. Niranjana Kumar, S.P. Singh, J. Kotesh Kumar, K.V.N.S. Srinivas, G. Krishna Mohan, K.P. Sastry and P. Grover. Isolation, Characterization and Biological Evaluation of Sophora interrupta Bedd. Proceedings of Andhra Pradesh Akademi of Sciences. 2014, 16(1), 85-93.

2013:

  1. Sastry KP, Kumar RD, Karnati K, Kumar AN., Kumar RR. Effect of Sowing Dates on Morphological Characteristics, Root Yield and Chemical Composition of the Root of Withania Somnifera Grown in the Semi-Arid Regions of Andhra Pradesh, India. Journal of Scientific Research and Reports, 2013, 2:121132.
  2. Sastry KP, Kumar RD, Kumar AN. Influence of different levels of gypsum on growth, herb and essential oil yields of lemongrass. Albanian Journal of agricultural sciences, 2013, 12:471-478.
  3. Pandu Sastry Kakaraparthi, Dharmendra Kumar Rajput, and A. Niranjan Kumar. Response of Java citronella (Cymbopogon winterianus jowitt) to sulphur fertilization in the semi arid tropical region in India. Scientific Journal of Crop Science, 2013, 2(6) 67-74.3
  4. Rao BRR, Syamasundar KV. Millettia pinnata (L.) Panigrahi: Overview and biological properties of fixed oil. In Bhattacharya S. Recent Progress in Medicinal Plants, Volume 33: Fixed Oils and Fats. (2, 123-144). Houston, USA.
  5. Rashmi Tiwari, Ashutosh Awasthi, Maneesha Mall, Ashutosh K. Shukla, K.V.N.S. Srinivas, K. V. Syamasundar and Alok Kalra, Bacterial endophyte-mediated enhancement of in planta content of key terpenoid indole alkaloids and growth parameters of Catharanthus roseus. Industrial Crops and Products, 2013, 43, 306-310.
  6. K. Baskaran, K.V.N.S. Srinivas and R. N. Kulkarni, Two induced macro-mutants of periwinkle with enhanced contents of leaf and root alkaloids and their inheritance. Industrial Crops and Products, 2013, 43, 701-703.
  7. Yakaiah Chinthala, Anand Kumar Domatti, Alam Sarfaraz, Singh Shailendra Pratap, Niranjan Kumar Arigari, Gupta Namita, Srinivas KVN. Satya, Kotesh Kumar Jonnala, Khan Feroz, Ashok K. Tiwari, Grover Paramjit. Synthesis, biological evaluation and molecular modeling studies of some novel thiazolidinediones with triazole ring: European Journal of Medicinal Chemistry, 2013, 70, 308-14.
  8. Niranjan Kumar A, Satya Srinivas KVN, Kotesh Kumar J and Sastry KP. Rare Cyano Glucosides from Coldenia procumbens Linn.: Journal of Chemical and Pharmaceutical Research, 2013, 5(12), 1394-97.

2012:

  1. Adinarayana G, Rahul G, Ravi KS, Syamasundar KV, Rao BRR. Evalauation of Antimicrobial Potential of Field Distilled and Water-Soluble Essential Oils of Cymbopogon flexuosus. Journal of Pharmacognosy, 2012, 3:142-146.
  2. Kulkarni SS, Ravindra NS, Srinivas, KVNS, Kulkarni RN. 2012. In vitro chemical mutagenesis in exclusively vegetatively-propagated rose-scented geranium (Pelargonium spp.) Natural Product Communications, 2012, 7:1223-1224.
  3. Naidu RC, Kumar AN, Komuraiah B, Srinivas, KVNS, Kumar JK, Ramakrishna KVS, Nayak VL, Ramakrishna S. Fatty acid derivatives from seeds of Annona squamosa Linn. Journal of Chemical and Pharmaceutical Research, 2012, 4:4558-4561.
  4. Rao BRR. Hydrosols and water-soluble essential oils of aromatic plants: Future economic products. Indian Perfumer,2012, 56:29-33.
  5. Rao BRR. Medicinal and aromatic plants processing technologies of Council of Scientific and Industrial Research (CSIR) institutions. Journal of Pharmacognosy, 2012, 3:138-141.
  6. Rao BRR, Rajput DK, Nagaraju G, Adinarayana G. Biotechnological interventions in Withania somnifera (L.) Dunal, Journal of Pharmacognosy, 2012, 3:88-91.
  7. Rao BRR, Rajput DK, Nagaraju G, Adinarayana G. Scope and Potential of Medicinal and Aromatic Plants products for Small and Medium Enterprises. Journal of Pharmacognosy, 2012, 3:112-114.
  8. Rao BRR, Syamasundar KV, Rajput DK, Nagaraju G, Adinarayana G. Biodiversity, Conservation and Cultivation of Medicinal Plants. Journal of Pharmacognosy, 2012, 3:59-62.
  9. Rao BRR, Syamasundar KV, Rajput DK, Nagaraju G, Adinarayana G. Potential Species of Medicinal Plants for Cultivation in Deccan Region, Journal of Pharmacognosy, 2012, 3:96-100.
  10. K.V. Syamasundar, G.Vinod, K.V.N.S. Srinivas and B.Srinivasulu, A New diterpenoid from Plectranthus bishopianus Benth. Helvicta Chemica Acta, 2012.
  11. S.K. Swaroop, N.S. Ravindra, K.V.N.S. Srinivas and R.N Kulkarni, A somaclonal variant of geranium (Pelargonium sp.) with similar contents of isomenthone and total alcohols in its essential oil. Nat. Prod. Commun, 2012, 7 (9), 1223-1224.
  12. Sastry KP, Kumar RD, Kumar N, Sneha G, Elizabeth M. Morpho-Chemical Description and Antimicrobial Activity of Different Ocimum Species. Journal of Plant Development, 2012, 19:53-64.

2011:

  1. R. Ramesh Kumar, L. Prasanna Anjaneya Reddy, J. Chinna Subbaiah, A. Niranjana Kumar, H.N. Nagendra Prasad and Balakishan Bhukya. Genetic association among root morphology, root quality and root yield in ashwagandha (Withania somnifera). Genetika, 2011, Vol 43, No.3, 617-624.
  2. R. Ramesh Kumar, Reddy L.P.A, Niranjana Kumar, A., Komaraiah, K. Purnanand, S. and K.P. Sastry. (2011). Root textural quality in ashwagandha (Withania somnifera) as influenced by crop growth periods and morphotypes. Industrial Crops and Products 2011, 34, 1231-1234.
  3. Rajeswara Rao BR and Rajput DK. Response of palmarosa {Cymbopogon martinii (Roxb.) Wats. var. motia Burk.} to foliar application of magnesium and micronutrients. Industrial Crops and Products, 2011, 33: 277-281.
  4. Rajeswara Rao BR, Rajput DK and Mallavarapu GR. Chemical diversity in curry leaf (Murraya koenigii) essential oils. Food Chemistry, 2011, 126: 989-994.
  5. Priyanka Trivedi, Jonnala Kotesh Kumar, Arvind Singh Negi, Karuna Shanker HPLC method development and validation of cytotoxic agent phenyl-heptatriyne in Bidens pilosa with ultrasonic-assisted cloud point extraction and preconcentration: Biomedical Chromatography, 2011, 25(6), 697-706.
  6. Debabrata Chanda, Dharmendra Saikia, J.K. Kumar, Jay Prakash Thakur, Jyoti Agarwal, C.S. Chanotiya, Karuna Shanker, Arvind S. Negi. 1-Chloro-2-formyl indenes and tetralenes as antitubercular agents: Bioorganic & Medicinal Chemistry Letters, 2011, 21(13), 3966-3969.
  7. Indra Sandal, Amita Bhattacharya, Uksha Saini, Devinder Kaur, Shveta Sharma, Ashu Gulati, Jonnala K Kumar, Neeraj Kumar, Jyotsna Dayma, Pralay Das, Bikram Singh and Paramvir S Ahuja. Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound: BMC Chemical Biology, 2011, 11:1.

2010:

  1. K.V. Syamasundar, B. Sravan Kumar, S.Srikanth, K.V.N.S. Srinivas and R.R. Rao, Limonia acidissima. A Rich Source of β-Pinene, from the Western Ghats of India. Chemistry of Natural Compounds, 2010, 46(3), 486.
  2. Rajeswara Rao BR, Rajput DK, Patel RP and Purnan S. Essential Oil Yield and Chemical Composition Changes during Leaf Ontogeny of Palmarosa (Cymbopogon martinii var. motia) Natural Product Communications, 2010, 5: 1947-1950.
  3. Rajeswara Rao BR, Kothari SK, Rajput DK, Patel RP and Sastry KP. Composition of rosemary (Rosmarinus officinalis L.) oil produced from the semi-arid tropical climate of south India. Journal of Medicinal and Aromatic Plant Sciences, 2010, 32: 20-23.

CSIR TECHNOLOGY AWARD FOR LIFE SCIENCES-2015:

Development of improved varieties and promotion of cultivation of Medicinally important Ashwagandha for improving the Economy of small and marginal farmers in semi-arid tropical (sat) regions of deccan plateau.


Ashwagandha - A potent medicinal plant

Withania somnifera [Family: Solanaceae] commonly known as ‘Ashwagandha’ is one of the most important medicinal plants used in various traditional systems of medicine as an aphrodisiac, rejuvenative and life prolonging agent. The plant contains chemical compounds called Withanolides /steroidal lactones to which most of the pharmacological activity is attributed. The dried roots of ashwagandha are the primary economic part and the starch and fibre contents play a dominant role in determining root quality. Brittle roots having high starch and low fibre are highly priced. In India, the plant grows wild in Northwestern regions extending to mountainous regions of Punjab, Himachal Pradesh and Jammu up to an altitude of 1500 m. It is also cultivated in thousands of hectares in Rajasthan, Madhya Pradesh and Andhra Pradesh.


Small and marginal farmers need crop diversification

In India about 60% of the cultivable area is under rainfed farming (rainfed agriculture contributes to 40% of the total food production). In the semi-arid to arid Central and Southern States, comprising Madhya Pradesh, Maharashtra, Andhra Pradesh, Karnataka and Tamil Nadu, about 76-82% of the total area under cultivation is under rainfed agriculture. Successive years of deficit/ delayed rainfall and/or failure of monsoon affect millions of farm holdings/families in this region.

In Andhra Pradesh, Anantapur is the largest district with majority of the population is rural based whose principal occupation is agriculture. Anantapur district was found to be one of the driest parts of the country with second lowest average rainfall of 520.4 mm and aridity index of 72.5% (Classified as tropical arid region with low rainfall after Jaisalmer district in Rajasthan). Ananthapur district made a historical switch over to groundnut leaving behind the cultivation of traditional crops in the early eighties. But the groundnut dream didn’t last forever. Problems started in the late nineties when the oil market was deregulated and the farmers were left high and dry in the light of import of palm oil. The search for alternative crops to replace groundnut led the farmers to CSIR-CIMAP during 2005-06 (a group of farmers led by an Ayurvedic doctor). Based on the information provided by the CIMAP Resource Centre, Hyderabad, the farmers started pilot scale cultivation of aswagandha during 2005-06, under the technical guidance of CRC, Hyderabad in a modest area. To improve the farmers income, CIMAP RC Hyderabad has took the challenge of introducing the high yielding varieties developed by CIMAP in place of low yielding wild varieties. Multi-disciplinary teams coordinated to develop a agrotechnologies suitable to the region and the economic advantage of CSIR-CIMAP varieties was demonstrated. Quality seed of the improved varieties was multiplied and made available to the farmers at subsidised rates, market linkages were established and promoted the cultivation in the SAT areas of Andhra Pradesh.

Cultivation of CSIR-CIMAP variety helped the small and marginal farmers economically in the SAT regions of the Deccan plateau and the area under cultivation reached 10,000 acres leading to a production of 1500 tons of dry root, 750 tons of seed and 750 tons of dry herbage all of which have market demand between 2007 and 2014. With this production level farmers today started earning a profit of Rs. 25,000 - 35,000/acre which is several times more than they get from traditional crops like groundnut or bengalgram.

The Centre has been recognized and conferred with CSIR-Technology Award for the year 2015 by Ministry of Science and Technology, Government of India.

Er. GD Kiran Babu Scientist In-charge
Phone : +91-40-27201131, 27200272
Email: crchyd[at]cimap[dot]res[dot]in
Address : CSIR-CIMAP Research Centre,
Post office Boduppal, Hyderabad - 500092,
Andhra Pradeh India