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Bioprospection and Product Development


Research work is carried out for ‘Bioprospecting natural resources for bioactive molecules and value-added products for the better health and life’. The focus is on finding the solutions for drug resistant infections (bacterial, fungi, and malaria parasite) and metabolic disorders like hepatoprotection, inflammation, immune-modulation, cancer etc. The efforts are also directed towards finding the safety limits of herbal preparations/products. Work is also carried out for the synthesis of novel plant-based nanomaterials and its application in the area of drug delivery specific focus on phytochemicals. Development of herbal formulations based on identified scientific leads and traditional knowledge base is undertaken by the division.

The other areas of research are:
Safety evaluation (in vivo/in silico) of MAPs and their products. Acute (single exposure), sub-acute (28 days repeated exposure) and sub chronic (90 days repeated exposure) oral toxicity and dermal toxicity. ADME study of plant based novel molecules. Synthesis of novel plant-based nanomaterials and its application in the area of drug delivery specific focus on phytochemicals. Novel medicinal plant derived molecules and extracts are being explored using ex-vivo, in-vitro and in-vivo models with major emphasis on role of ion channels, protein kinases, AT1 blockade etc. as a mechanism of action. Drug Delivery systems (nano-emulsion, nano-particles, micelles, liposomes) of plant drugs for (Diabetes, Psoriasis, Hepatoprotection) etc.

Scientists