Name : Rajesh Chandra Misra Designation : Scientist-D Address : CSIR-Central Institute of Medicinal and Aromatic Plants, P.O-CIMAP, Near Kukrail Picnic Spot, Lucknow-226015, Uttar Pradesh, India E. mail : rcmisra[dot]cimap[at]csir[dot]res[dot]in Contact No : 9389223806 Epabx No. : 0000 Download Resume Area of Specialization Plant Biochemistry and Biotechnology, Specialized Metabolism, Synthetic Biology, Metabolomics, Metabolic Engineering, Plant Cell Culture, Plant-Insect Interaction and Plant-Defense Response Education B.Tech. Biotechnology M.Tech. Biotechnology Ph.D. Plant Biochemistry and Biotechnology Academic/Research Experience John Innes Centre, Norwich, United Kingdom, Department of Biochemistry and Metabolism - Post-doctoral Scientist (May 2018- January 2025 ) National Physical Laboratory, Teddington, United Kingdom, Department of Chemical and Biological Sciences - Higher Scientist (January 2025- March 2026 ) CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP), Plant Biotechnology - Scientist-D (March 2026- till date ) Honours and Awards Young Scientist Platinum Jubilee Award,by The National Academy of Sciences, India (NASI) in 2019 Outstanding Publication Award,by CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP) in 2019 INSPIRE Faculty Award,by Department of Science & Technology in 2018 Outstanding Publication Award,by CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP) in 2018 Outstanding Publication Award,by CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP) in 2017 Outstanding Publication Award,by CSIR-Central Institute of Medicinal and Aromatic Plants (CIMAP) in 2014 Senior Research Fellowship,by The Council for Scientific and Industrial Research in 2013 Publication Rajesh Chandra Misra, Amr El-Demerdash, Amir Ronen, Oria Teena, Charlotte Owen, Benjamin D. Scott, Andrew Steed, Barrie Wilkinson, Paul Nicholson, Guy Polturak, Anne Osbourn. Diverse Diterpenoid Phytoalexins Shape Wheat Chemical Defenses. bioRxiv 2026 Yuzhong Liu, Fei Gan, Xiaoyue Chen, Samantha Crowe, Graham Hudson, Michael Belcher, Matthias Schmidt, Xixi Zhao, Maria Astolfi, Bo Pang, Minglong Shao, Jing Yin, Sasilada Sirirungruang, James Reed, Laetitia Martin, Amr El-Demerdash, Shingo Kikuchi, Rajesh Chandra Misra, Michael Cronce, Xiulai Chen, Chunjun Zhan, Ramu Kakumanu, Edward Baidoo, Kai Deng, Yan Chen, Christopher Petzold, Anne Osbourn, Henrik Scheller, Jay D Keasling. Complete biosynthesis of QS-21 in engineered yeast. Nature 2024 Laetitia Martin, Shingo Kikuchi, Martin Rejzek, Charlotte Owen, James Reed, Anastasia Orme, Rajesh Chandra Misra, Amr El-Demerdash, Lionel Hill, Hannah Hodgson, Yuzhong Liu, Jay D Keasling, Robert Field, Andrew Truman, Anne Osbourn. Complete biosynthesis of the potent vaccine adjuvant QS-21. Nature Chemical Biology 2024 James Reed, Anastasia Orme, Amr El-Demerdash, Charlotte Owen, Laetitia B.B. Martin, Rajesh Chandra Misra, Shingo Kikuchi, Martin Rejzek, Azahara C. Martin, Alex Harkess, Jim Leebens-Mack, Thomas Louveau, Michael J. Stephenson1, Anne Osbourn. Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree. Science 2023 Guy Polturak, Rajesh Chandra Misra, Amr El-Demerdash, Charlotte Owen, Andrew Steed, Hannah McDonald, JiaoJiao Wang, Gerhard Saalbach, Carlo Martins, Barrie Wilkinson, Paul Nicholson, Anne Osbourn. Discovery of Isoflavone Phytoalexins in Wheat Reveals a Unique Route to Isoflavonoid Biosynthesis. Nature Communications 2023 Guy Polturak, Martin Dippe, Michael J. Stephenson, Rajesh Chandra Misra, Charlotte Owen, Ricardo H. Ramirez-Gonzalez, John F. Haidoulis, Henk-Jan Schoonbeek, Laetitia Chartrain, Philippa Borrill, David R. Nelson, James K.M. Brown, Paul Nicholson, Cristobal, Anne Osbourn. Pathogen-induced biosynthetic pathways encode defense-related molecules in bread wheat. The Proceedings of the National Academy of Sciences (PNAS) USA 2022 Ramesha Thimmappa, Shi Wang, Minyan Zheng, Rajesh Chandra Misra, Ancheng C. Huang, Gerhard Saalbach, Yaqing Chang, Zunchun Zhou, Veronica Hinman, Zhenmin Bao, Anne Osbourn. Biosynthesis of saponin defensive compounds in sea cucumbers. Nature Chemical Biology 2022 Payal Srivastava, Anchal Garg, Rajesh Chandra Misra, Chandan Singh Chanotiya, Sumit Ghosh. UGT86C11 is a novel plant UDP-glycosyltransferase involved in labdane diterpene biosynthesis. Journal of Biological Chemistry 2021 Rajesh Chandra Misra , Shubha Sharma, Anchal Garg, Sumit Ghosh. Virus-Induced Gene Silencing in Sweet Basil (Ocimum Basilicum). Methods in molecular biology (Clifton, NJ) 2020 Gaurav Srivastava, Sandeep, Anchal Garg, Rajesh Chandra Misra, Chandan Singh Chanotiya, Sumit Ghosh. Transcriptome analysis and functional characterization of oxidosqualene cyclases of the arjuna triterpene saponin. Plant Science 2020 Sandeep, Rajesh Chandra Misra, Chandan Singh Chanotiya, Pradipto Mukhopadhyay, Sumit Ghosh. Oxidosqualene cyclase and CYP716 enzymes contribute to triterpene structural diversity in the medicinal tree banaba. New Phytologist 2019 Rajesh Chandra Misra, Shubha Sharma, Sandeep, Anchal Garg, Chandan Singh Chanotiya, Sumit Ghosh. Two CYP716A subfamily cytochrome P450 monooxygenases of sweet basil play similar but nonredundant roles in ursane- and oleanane-type pentacyclic triterpene biosynthesis. New Phytologist 2017 Rajesh Chandra Misra, Sandeep, Mohan Kamthan, Santosh Kumar, Sumit Ghosh. A thaumatin-like protein of Ocimum basilicum confers tolerance to fungal pathogen and abiotic stress in transgenic. Scientific Reports 2016 Anchal Garg, Lalit Agrawal, Rajesh Chandra Misra, Shubha Sharma, Sumit Ghosh. Andrographis paniculata transcriptome provides molecular insights into tissue- specific accumulation of medicinal diterpenes. BMC Genomics 2015 Rajesh Chandra Misra, Anchal Garg, Sudeep Roy, Chandan Singh Chanotiya, Prema G Vasudev, Sumit Ghosh. Involvement of an ent-copalyl diphosphate synthase in tissue-specific accumulation of specialized diterpenes in Andrographis paniculata. Plant Science 2015 Rajesh Chandra Misra, Protiti Maiti, Chandan Singh Chanotiya, Karuna Shanker, Sumit Ghosh. Methyl jasmonate-elicited transcriptional responses and pentacyclic triterpene biosynthesis in sweet basil. Plant Physiology 2014 Rajesh Chandra Misra, Atul Kumar Verma, Shiv Kumar Verma, Vikas Kumar, Waseem Ahmad Siddiqui, Mohd Imran Siddiqi, Puvvada Kalpana Murthy. Heat shock protein 60 of filarial parasite Brugia malayi: cDNA cloning, expression, purification and in silico modeling and analysis of its ATP binding site. Experimental Parasitology 2012 Patents File No Title Inventors Patent No. Abstract